A simple microfluidic platform to study age-dependent protein abundance and localization changes in Saccharomyces cerevisiae

April 13, 2017

We have developed a user-friendly microfluidic system paired with a genetic approach to enrich and study ageing mother yeast cells, enabling the monitoring of protein abundance and localization changes during the crucial first half of their replicative lifespan, leading to the discovery of novel age-dependent protein behaviors.