Optogenetic monitoring identifies phosphatidylthreonine-regulated calcium homeostasis in Toxoplasma gondii
May 1, 2016
Toxoplasma gondii is an obligate intracellular parasite, which inflicts acute as well as chronic infections in a wide range of warm-blooded vertebrates. Using an optogenetic sensor to monitor subcellular calcium in this model intracellular pathogen we found a novel regulatory function of phosphatidylthreonine in calcium signaling.
Phosphatidylthreonine: An exclusive phospholipid regulating calcium homeostasis and virulence in a parasitic protist
May 1, 2016
This article comments on work published by Kuchipudi et al. (Microbial Cell, 2016), which describes the role of phohsphatidylthreonine in the regulation of calcium homeostasis and virulence in the protozoan parasite Toxoplasma gondii.