Inhibitors of glycosomal protein import provide new leads against trypanosomiasis
July 3, 2017
This article comments on work published by Dawidowski et al. (Science, 2017), which provides the grounds for further development of the glycosome inhibitors into clinical candidates and validates the parasite protein-protein interactions as drug targets.
Advancing host-directed therapy for tuberculosis: new therapeutic insights from the Toxoplasma gondii
March 2, 2017
This article comments on work published by Koh et al. (PLoS Pathog, 2017), which uncovered that infection-induced signaling pathways suggest possibilities for the development of novel therapeutic modalities for TB that target the intracellular signaling pathways permitting the replication of Mycobacterium tuberculosis (MTB).