Massive gene swamping among cheese-making Penicillium fungi

March 3, 2014

This article comments on work published by Cheeseman et al. (Nat Comm, 2014), which indicates that horizontal gene transfer is a crucial mechanism of rapid adaptation, even among eukaryotes.

Salt stress causes cell wall damage in yeast cells lacking mitochondrial DNA

March 3, 2014

In this work, the authors report that salt stress causes cell wall damage in yeast cells lacking mitochondrial DNA (ρ0) and that this damage is related to elevated levels of SCW11 and salt stress-induced reactive oxygen species.

Deletion of AIF1 but not of YCA1/MCA1 protects Saccharomyces cerevisiae and Candida albicans cells from caspofungin-induced programmed cell death

January 15, 2014

This work suggests that deleting AIF1 but not YCA1/MCA1 protects S. cerevisiae and Candida albicans from caspofungin-induced cell death. This is not only the first time that AIF1 has been specifically tied to cell death in Candida but also the first time that caspofungin resistance has been linked to the cell death machinery in yeast.

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