Neutralizing the threat: harnessing broadly neutralizing antibodies against HIV-1 for treatment and prevention

July 3, 2024

This review provides an overview of the advancements in HIV- 1-specific broadly neutralizing antibodies and discusses the insights gathered from recent clinical trials regarding their application in treating and preventing HIV-1 infection.

Biofilms by bacterial human pathogens: Clinical relevance – development, composition and regulation – therapeutical strategies

February 1, 2021

This review focuses on bacterial biofilms formed by human pathogens, highlights their relevance for diverse diseases and discusses therapeutical intervention strategies targeting biofilms.

Chlamydia trachomatis Genital Infections

September 4, 2016

Chlamydia trachomatis infections are the most commonly reported sexually transmitted bacterial infections in the US and globally. Ascending infection may result in infertility, ectopic pregnancy and chronic pelvic pain in some women. In this review we provide an overview of current knowledge regarding epidemiology, disease outcomes and effective treatment of chlamydial genital tract infection and explore potential mechanisms facilitating C. trachomatis infection of genital mucosa identified via bioinformatics and other molecular approaches.

Recent Insights into the HIV/AIDS Pandemic

September 4, 2016

Acquired immunodeficiency syndrome (AIDS), caused by chronic infection with the human immunodeficiency virus1 (HIV-1), is one of the most devastating pandemics ever recorded in human history. In this review, we assemble new details on the molecular events from the attachment of the virus, to the assembly and release of the viral progeny.